Hereditary hemochromatosis: Retrospective study on clinical data from Emergency County Hospital Mures

Abstract Objective : Hereditary hemochromatosis, or primary is a recessive genetic liver disorder caused by iron accumulation in tissues. This study evaluates patients with hereditary hemochromatosis to determine correlations between clinical and laboratory data. Methods The data analyzed this was gathered from the discharge records 2019 2021 of Gastroenterology Department Mures Country Emergency Clinical Hospital. 15 were sampled during studied period. Results Hepatic cirrhosis present 67% group patients, 40% presented hypertension 20% showed diabetes mellitus portal hypertension. Positive obtained serum alkaline phosphatase (r=0.8536), lactate dehydrogenase (r=0.7381), urea (r = 0.79). Positive, strong correlation ferritin (r=0.7719), GOT (r=0.778) GPT (r=0.6108). total bilirubin direct 0.85), 0.68) 0.82). Conclusions Excess stored influencing organ function trough reactive oxygen species, hepatic signs being main participant presentation, while cause damage other tissues such as myocardium, pancreas kidneys. Treatment for includes phlebotomies, chelation Deferoxamine.